Cohort Confounders: Inaccuracies in Genetic Tests & What to Do About It
Time: 10:00 am
day: Day One
• Biomarker discovery – Finding the needle in the haystack through ACCURATE genetics/genomics
• Looking at what can go wrong in cohorts identified through genetic/ genomic testing – In the discovery phase, how can you recruit people with a specific phenotype/genotype so you can discover the genomic basis for a specific phenotype (application in germline, neuro and oncology)
• Basis for a good laboratory partner: Pre-screening of labs
• Cohorts and clinical design: What positives are you accepting in the clinical setting?