Using Longitudinal Data to Understand How a Biomarker Behaves

Time: 10:00 am
day: Day Two


• Design and execution of a natural history study to obtain a more holistic picture of disease
• Avoiding bias, by investigating possible prognostic, stratification, disease relevant biomarkers as part of a study
• Measuring target engagement in accessible biofluids, particularly using information from CSF exosomes, to collect evidence for pharmacological effect